Description

2-Bromo-n-(Prop-2-Yn-1-Yl)Acetamide is a specialized bromoacetamide derivative featuring a terminal alkyne functional group, making it a versatile and highly reactive building block for advanced organic synthesis. Its core value lies in enabling efficient click chemistry and cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for drug discovery, polymer modification, and the development of novel chemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne-azide cycloaddition (click chemistry) for bioconjugation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators by serving as an alkylating agent or a linker for bioactive molecules.
• Material Science & Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating specialty polymers, coatings, and hydrogels with tailored properties.
• Bioconjugation & Probe Synthesis: Essential for labeling biomolecules (proteins, peptides, nucleic acids) with fluorescent or affinity tags via its reactive bromo and alkyne groups.
• Organic Synthesis Building Block: Employed in palladium-catalyzed Sonogashira couplings and other metal-mediated reactions to introduce acetylene-functionalized acetamide motifs.
• Chemical Biology Tool: Used to develop activity-based probes (ABPs) for studying enzyme function and mechanism in proteomic research.

Basic Information

Product Name	2-Bromo-n-(Prop-2-Yn-1-Yl)Acetamide
CAS No.	173208-24-7
Molecular Formula	C5H6BrNO
Molecular Weight	176.01 g/mol
Synonyms	N-(Prop-2-yn-1-yl)-2-bromoacetamide; 2-Bromo-N-(2-propynyl)acetamide; Propargyl Bromoacetamide; Bromoacetamide Propargyl Derivative; N-Propargyl-2-bromoacetamide; 2-Bromoacetamide Propargyl Ester; Bromoacetic Acid Propargylamide
EINECS	Contact for details

Quality Control

Our 2-Bromo-n-(Prop-2-Yn-1-Yl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and to support your research and production quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.