Description

1,3-Cyclopentanediol,4,5-Difluoro-,Monoacetate,[1S-(1-α-,3-α-,4-Bta-,5-Bta-)]-(9Ci) is a high-purity, stereochemically defined fluorinated cyclopentane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a diol moiety protected as a monoacetate and strategically placed fluorine atoms, makes it invaluable for modulating the physicochemical properties and biological activity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel antiviral, anticancer, and central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine substitution is leveraged for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or modifier for creating specialty polymers with unique thermal and surface properties.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research into the effects of gem-difluoro substitution on cycloalkane ring systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthesis projects.

Basic Information

Item	Details
Product Name	1,3-Cyclopentanediol,4,5-Difluoro-,Monoacetate,[1S-(1-α-,3-α-,4-Bta-,5-Bta-)]-(9Ci)
CAS No.	173141-11-2
Molecular Formula	C7H10F2O3
Molecular Weight	180.15 g/mol
Synonyms	(1S,3S,4R,5R)-4,5-Difluoro-1,3-cyclopentanediol Monoacetate; (1S,3S,4R,5R)-4,5-Difluorocyclopentane-1,3-diol Monoacetate; 4,5-Difluoro-1,3-cyclopentanediol Monoacetate (1S,3S,4R,5R)-; [1S-(1α,3α,4β,5β)]-4,5-Difluoro-1,3-cyclopentanediol Monoacetate; Fluorinated Cyclopentanediol Monoacetate; Chiral Difluorocyclopentane Derivative; CAS 173141-11-2
EINECS	Contact for details

Quality Control

Every batch of our 1,3-Cyclopentanediol,4,5-Difluoro-,Monoacetate is produced under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to ensure excellent enantiomeric purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from strong alkalis and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.