Description

1H-Imidazole-4-Acetonitrile,4,5-Dihydro-1-Methyl-(9Ci) is a specialized heterocyclic nitrile building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for the development of novel pharmacologically active molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical companies for synthesizing complex heterocycles, enzyme inhibitors, and other high-value fine chemicals. Its unique imidazoline-acetonitrile structure offers versatile reactivity for constructing targeted molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Employed in the design of probes and linkers for bioconjugation and diagnostic applications.
• Material Science: Utilized in the research and development of advanced polymers and functional organic materials.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and corporate R&D labs.

Basic Information

Product Name	1H-Imidazole-4-Acetonitrile,4,5-Dihydro-1-Methyl-(9Ci)
CAS No.	172938-94-2
Molecular Formula	C6H9N3
Molecular Weight	123.16 g/mol
Synonyms	4,5-Dihydro-1-methyl-1H-imidazole-4-acetonitrile; 1-Methyl-4,5-dihydro-1H-imidazole-4-acetonitrile; 1-Methyl-2-imidazoline-4-acetonitrile; 4-(Cyanomethyl)-1-methyl-4,5-dihydro-1H-imidazole; 1-Methyl-δ²-imidazoline-4-acetonitrile; 172938-94-2; 4,5-Dihydro-1-methylimidazole-4-acetonitrile
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-4-Acetonitrile,4,5-Dihydro-1-Methyl-(9Ci) is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.