Description

N,n-Di-Boc-4-Aminomethyl Benzonitrile is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating complex multi-step reactions, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where protecting group chemistry is essential. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and specialty chemical producers engaged in peptide synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis of peptides and peptidomimetics where the Boc-protected amine group is required for selective coupling.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Organic Synthesis Reagent: Employed in multi-step synthetic sequences requiring a protected aromatic aminomethyl functionality.
• Agrochemical Development: Utilized as an intermediate in the research and production of advanced crop protection agents.
• Material Science Precursor: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced materials.

Basic Information

Product Name	N,n-Di-Boc-4-Aminomethyl Benzonitrile
CAS No.	172348-74-2
Molecular Formula	C19H26N2O4
Molecular Weight	346.42 g/mol
Synonyms	4-((Bis(tert-butoxycarbonyl)amino)methyl)benzonitrile; 4-(Bis(tert-butoxycarbonylamino)methyl)benzonitrile; 4-((Di-tert-butoxycarbonylamino)methyl)benzonitrile; 4-(N,N-Bis(tert-butoxycarbonyl)aminomethyl)benzonitrile; 4-(Bis-Boc-aminomethyl)benzonitrile; Di-Boc-4-cyanobenzylamine; 1,1-Dimethylethyl N-[4-(cyanophenyl)methyl]-N-[(1,1-dimethylethoxy)carbonyl]carbamate
EINECS	Contact for details

Quality Control

Our N,n-Di-Boc-4-Aminomethyl Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee supply consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.