Description

Trifluoroacetamide,-(4-Bromobenzyl) CAS NO 172218-35-8 is a high-purity, halogenated acetamide derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a trifluoroacetyl group and a bromobenzyl moiety, makes it a versatile intermediate for introducing specific functional groups and modifying molecular properties. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl and aryl bromide groups.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Intermediate in the synthesis of monomers or additives for advanced polymers with specific thermal or chemical resistance properties.
• Fluorine Chemistry: A valuable source of the trifluoroacetamide group for introducing fluorine atoms into target molecules to enhance metabolic stability and lipophilicity.
• Cross-Coupling Reactions: The bromobenzyl group acts as a handle for versatile palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions.

Basic Information

Product Name	Trifluoroacetamide,-(4-Bromobenzyl)
CAS No.	172218-35-8
Molecular Formula	C9H7BrF3NO
Molecular Weight	282.06 g/mol
Synonyms	N-(4-Bromobenzyl)-2,2,2-trifluoroacetamide; 4-Bromobenzyltrifluoroacetamide; 2,2,2-Trifluoro-N-(4-bromobenzyl)acetamide; α,α,α-Trifluoro-N-(p-bromobenzyl)acetamide; N-(p-Bromobenzyl)trifluoroacetamide; N-(4-Bromophenylmethyl)trifluoroacetamide; Trifluoroacetic acid (4-bromobenzyl)amide; (4-Bromobenzyl)trifluoroacetamide
EINECS	Contact for details

Quality Control

Our Trifluoroacetamide,-(4-Bromobenzyl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.