Description

Cyclic Iodixanol (90%) is a high-purity, non-ionic, water-soluble contrast agent intermediate. This compound is critical for the synthesis of advanced X-ray and CT imaging media, offering excellent osmolality control and biocompatibility. It is primarily required by pharmaceutical manufacturers and fine chemical suppliers serving the diagnostic imaging and medical research sectors. Consistent quality and reliable supply are paramount for these high-value applications.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of Iodixanol, a widely used iso-osmolar contrast medium.
• Diagnostic Imaging: Production of non-ionic, dimeric contrast agents for enhanced visualization in angiography, urography, and computed tomography (CT).
• Research & Development: Used in academic and industrial labs for developing new contrast media with improved safety and efficacy profiles.
• Fine Chemical Synthesis: Serves as a versatile building block for other iodinated compounds in specialty chemistry.
• Biomedical Studies: Employed in preclinical studies to understand the pharmacokinetics and biodistribution of contrast agents.
• Quality Control Reference: Acts as a reference standard for the analysis and quality assurance of final contrast agent formulations.

Basic Information

Product Name	Cyclic Iodixanol (90%)
CAS No.	171897-73-7
Molecular Formula	C35H44I6N6O15
Molecular Weight	1550.18 g/mol
Synonyms	5,5'-[(2-Hydroxy-1,3-propanediyl)bis(acetylamino)]bis[N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide]; Iodixanol Cyclic Intermediate; 1,3-Bis(acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-hydroxy-1,3-propanediyl)bis(acetylamino)]-isophthalamide Cyclic Form; Visipaque Intermediate; Cyclic Iodixanol Precursor
EINECS	Contact for details

Quality Control

Our Cyclic Iodixanol (90%) is manufactured under a strict quality management system. Each batch is tested to ensure it meets exacting standards for purity and consistency, suitable for use in pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, assay, impurity profile, and residual solvents is provided with every shipment. Our quality commitment aligns with cGMP principles to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	NLT 90.0%
Related Substances (HPLC)	Total impurities NMT 5.0% Any individual impurity NMT 1.0%
Water Content (KF)	NMT 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.