Description

Mitogen Activated Protein Kinase 2 Fragment 326-339 is a synthetic peptide fragment corresponding to a specific sequence of the MAPK2 protein, a key component in cellular signal transduction pathways. This high-purity reference standard is critical for biochemical research, enabling the study of kinase activity, protein-protein interactions, and signal cascade mechanisms. It is primarily utilized by researchers and developers in pharmaceutical R&D, academic biochemistry, and proteomics for assay development, target validation, and as a critical reagent in enzymatic studies.

Application

• Biochemical Research & Assay Development: Serves as a precise substrate or reference standard in enzymatic activity assays for MAPK2 and related kinases.
• Pharmaceutical R&D: Used in high-throughput screening (HTS) campaigns to identify and characterize novel kinase inhibitors for therapeutic development.
• Signal Transduction Studies: A key tool for investigating the MAPK/ERK pathway, cellular proliferation, differentiation, and stress responses.
• Antibody Production & Epitope Mapping: Acts as an immunogen or a target antigen for generating and screening specific antibodies.
• Proteomics & Protein Interaction Analysis: Employed in pull-down assays, surface plasmon resonance (SPR), and other techniques to study binding partners.
• Quality Control & Standardization: Provides a defined benchmark for the calibration and validation of analytical methods in a GLP/GMP environment.

Basic Information

Item	Detail
Product Name	Mitogen Activated Protein Kinase 2 Fragment 326-339
CAS No.	171869-94-6
Molecular Formula	C71H118N20O21S
Molecular Weight	1563.88 g/mol
Synonyms	MAPK2 (326-339); MAP Kinase 2 Fragment 326-339; ERK2 Fragment (326-339); p42 MAPK Fragment 326-339; Mitogen-Activated Protein Kinase 2 Peptide (326-339); Extracellular Signal-Regulated Kinase 2 Peptide Fragment; MK02 (326-339); PRKM1 Fragment
EINECS	Contact for details

Quality Control

Every batch of Mitogen Activated Protein Kinase 2 Fragment 326-339 is manufactured and tested under stringent quality management systems. Our products undergo rigorous analytical testing, including HPLC and MS, to ensure high purity (>95% typical) and identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with each shipment to support your research reproducibility and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.