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1,3,5-Tri-o-Benzoyl-2-Deoxy-2-Fluoro-α-L-Arabinofuranose CAS NO 171721-00-9


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CAS No.:171721-00-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3,5-Tri-o-Benzoyl-2-Deoxy-2-Fluoro-α-L-Arabinofuranose is a high-purity, protected nucleoside intermediate critical for advanced pharmaceutical synthesis. This compound serves as a key building block in the development of novel antiviral and anticancer therapeutics, particularly in the synthesis of modified nucleoside analogs. It is essential for research institutions and pharmaceutical manufacturers engaged in cutting-edge drug discovery and process development.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated nucleoside analogs for antiviral and anticancer drug candidates.
  • Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
  • Oncology Research: Serves as a building block for creating chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
  • Process Chemistry & Scale-Up: Employed in route scouting, optimization, and cGMP manufacturing for clinical trial material.
  • Biochemical Tool Development: Utilized to create labeled or modified nucleotides for molecular biology and diagnostic assays.
  • Academic & Contract Research: A valuable reagent for synthetic organic chemistry research in universities and CROs.

Basic Information

Product Name 1,3,5-Tri-o-Benzoyl-2-Deoxy-2-Fluoro-α-L-Arabinofuranose
CAS No. 171721-00-9
Molecular Formula C26H21FO7
Molecular Weight 464.44 g/mol
Synonyms 2-Deoxy-2-fluoro-1,3,5-tri-O-benzoyl-α-L-arabinofuranose; 2-Fluoro-2-deoxy-1,3,5-tri-O-benzoyl-α-L-arabinofuranose; 1,3,5-Tri-O-benzoyl-2-deoxy-2-fluoro-α-L-arabinofuranose; 2-Fluoro-2-deoxyarabinofuranose tribenzoate; α-L-2-Fluoro-2-deoxyarabinofuranose 1,3,5-tribenzoate; 2-F-ara-Furanose Tribenzoate; 171721-00-9; Tribenzoyl fluorinated arabinofuranose derivative
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Quality Control

Our 1,3,5-Tri-o-Benzoyl-2-Deoxy-2-Fluoro-α-L-Arabinofuranose is manufactured under strict quality systems suitable for pharmaceutical research. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete analytical data are provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry environment to minimize exposure to moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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