Description

Cyclobutanecarboxamide, 3-Amino-n-Methoxy-n-Methyl-, cis- (9Ci) is a specialized cis-configured cyclobutane derivative featuring both amino and methoxy-methyl amide functional groups. This compound is a high-value chemical intermediate prized for its rigid, strained ring structure, which is instrumental in the synthesis of complex, three-dimensional molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, where the cyclobutane ring can enhance biological activity and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science: Investigated as a monomer or cross-linking agent for producing polymers with unique thermal and mechanical properties due to the ring strain.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and protein-protein interactions in biochemical pathways.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and stereochemistry at universities and CROs (Contract Research Organizations).

Basic Information

Product Name	Cyclobutanecarboxamide, 3-Amino-n-Methoxy-n-Methyl-, cis- (9Ci)
CAS No.	171549-87-4
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	cis-3-Amino-N-methoxy-N-methylcyclobutanecarboxamide; N-Methoxy-N-methyl-cis-3-aminocyclobutanecarboxamide; cis-3-Amino-1-(methoxy(methyl)carbamoyl)cyclobutane; 3-Amino-N-methoxy-N-methylcyclobutanecarboxamide (cis-); Cyclobutanecarboxamide, 3-amino-N-methoxy-N-methyl-, (1r,3r)-rel-; (1r,3r)-3-Amino-N-methoxy-N-methylcyclobutanecarboxamide; CAS 171549-87-4
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxamide, 3-Amino-n-Methoxy-n-Methyl-, cis- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric/excess), and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.