Description

Cyclobutanecarboxamide, 3-Hydroxy-n-Methoxy-n-Methyl-, cis- (9Ci) is a specialized chiral building block featuring a functionalized cyclobutane ring system. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecules with precise stereochemistry. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Advanced Material Research: Serves as a precursor for specialty polymers or liquid crystals where the rigid cyclobutane core imparts specific material properties.
• Methodology Development: Employed in academic and industrial laboratories to develop new asymmetric synthesis or ring-formation methodologies.
• Peptidomimetics: The amide functionality and chiral centers make it a potential scaffold for designing peptide mimics in medicinal chemistry.
• Chemical Biology Probes: Useful for creating tool compounds to study biological pathways and enzyme functions.

Basic Information

Item	Details
Product Name	Cyclobutanecarboxamide, 3-Hydroxy-n-Methoxy-n-Methyl-, cis- (9Ci)
CAS No.	171549-81-8
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	cis-3-Hydroxy-N-methoxy-N-methylcyclobutanecarboxamide; (1R,3S)-3-Hydroxy-N-methoxy-N-methylcyclobutanecarboxamide; (1S,3R)-3-Hydroxy-N-methoxy-N-methylcyclobutanecarboxamide; N-Methoxy-N-methyl-cis-3-hydroxycyclobutanecarboxamide; cis-3-Hydroxy Weinreb amide of cyclobutanecarboxylic acid; Cyclobutanecarboxamide, 3-hydroxy-N-methoxy-N-methyl-, cis-; 171549-81-8
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxamide, 3-Hydroxy-n-Methoxy-n-Methyl-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.