Description

1,3-Difluoro-5-Methylsulfonylbenzene is a high-purity fluorinated aromatic sulfone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing sulfonyl and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its bioisosteric properties.
• Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and electronic materials requiring specific dielectric or thermal properties.
• Chemical Research: A versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing functional groups.
• Dye and Pigment Industry: Intermediate for synthesizing advanced fluorinated dyes and pigments with enhanced lightfastness and chemical stability.

Basic Information

Product Name	1,3-Difluoro-5-Methylsulfonylbenzene
CAS No.	171421-55-9
Molecular Formula	C7H6F2O2S
Molecular Weight	192.18 g/mol
Synonyms	3,5-Difluorophenyl Methyl Sulfone; 5-Methylsulfonyl-1,3-difluorobenzene; 1,3-Difluoro-5-(methylsulfonyl)benzene; 3,5-Difluorobenzene-1-sulfonyl Methyl; Benzene, 1,3-difluoro-5-(methylsulfonyl)-; 3,5-Difluorophenylmethanesulfonyl; Methyl 3,5-difluorophenyl sulfone
EINECS	Contact for details

Quality Control

Our 1,3-Difluoro-5-Methylsulfonylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.