Description

1-Ethynyl-3,5-Dimethoxybenzene (98%) is a high-purity aromatic acetylene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring an ethynyl group flanked by methoxy substituents, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to the development of functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds with acetylene-linked aromatic systems.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that require specific aromatic-alkyne motifs.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, dendrimers, and conductive organic materials.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated ligands for transition metal catalysts used in coupling reactions (e.g., Sonogashira, Glaser).
• Chemical Biology & Probe Development: Useful for creating molecular probes and tags via click chemistry (CuAAC) due to its terminal alkyne functionality.
• Organic Electronic Materials: A precursor for molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).

Basic Information

Product Name	1-Ethynyl-3,5-Dimethoxybenzene (98%)
CAS No.	171290-52-1
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	3,5-Dimethoxyphenylacetylene; 3,5-Dimethoxybenzeneacetylene; 3,5-Dimethoxyphenylethyne; 1-Ethynyl-3,5-dimethoxybenzene; 3,5-Dimethoxy-1-ethynylbenzene; (3,5-Dimethoxyphenyl)acetylene; 3,5-Dimethoxyphenyl ethyne
EINECS	Contact for details

Quality Control

Our 1-Ethynyl-3,5-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the declared purity and specification. A comprehensive Certificate of Analysis (COA) detailing purity (by GC/HPLC), identity confirmation (IR, NMR), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.