Description

S-Trityl-L-Cysteine-Benzylamide is a protected cysteine derivative, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is critical for introducing cysteine residues into peptide chains while preventing unwanted side reactions during the coupling process. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of L-cysteine into complex peptide sequences, particularly for disulfide bond formation.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) for peptide drugs targeting metabolic, oncological, and infectious diseases.
• Bioconjugation and Labeling: Used to introduce thiol-reactive handles onto peptides for site-specific conjugation with fluorophores, polymers, or drug payloads.
• Chemical Biology Research: Employed in the study of protein-protein interactions, enzyme mechanisms, and the development of peptide-based inhibitors or probes.
• Custom Peptide Manufacturing: A high-purity starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients.
• Protecting Group Strategy Development: Used in methodological research to explore novel protection and deprotection schemes in complex organic synthesis.

Basic Information

Product Name	S-Trityl-L-Cysteine-Benzylamide
CAS No.	171176-70-8
Molecular Formula	C29H28N2OS
Molecular Weight	452.61 g/mol
Synonyms	L-Cysteine, S-(triphenylmethyl)-, benzylamide; S-Trityl-L-cysteine benzyl amide; (S)-2-Amino-3-((tritylthio)propanoyl)benzylamide; N-Benzyl-S-trityl-L-cysteinamide; Fmoc-Cys(Trt)-NHBzl (Note: This is a related, protected form); S-Triphenylmethyl-L-cysteine benzylamide; Benzylamide of S-trityl-L-cysteine; Cysteine derivative, S-trityl protected, benzylamide
EINECS	Contact for details

Quality Control

Our S-Trityl-L-Cysteine-Benzylamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) with detailed batch-specific results are provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.