Description

2,3-Difluoro-4-Methoxyphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by pharmaceutical, agrochemical, and advanced materials research and development teams for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure contributes to desired electronic properties.
• Cross-Coupling Reactions: Serves as a versatile boronic acid reagent in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology & Probe Synthesis: Acts as a handle for bioconjugation and the synthesis of molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	2,3-Difluoro-4-Methoxyphenylboronic Acid
CAS No.	170981-41-6
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(2,3-Difluoro-4-methoxyphenyl)boronic acid; 2,3-Difluoro-4-methoxybenzeneboronic acid; 4-Methoxy-2,3-difluorophenylboronic acid; B-(2,3-Difluoro-4-methoxyphenyl)boronic acid; 170981-41-6; 2,3-Difluoro-4-methoxybenzeneboronic Acid; 2,3-Difluoro-p-anisylboronic acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.