Description

2-Fluoro-4-Methylphenylboronic Acid is a high-purity organoboron reagent, a crucial building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize active pharmaceutical ingredients (APIs), novel crop protection agents, and functional organic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in constructing biaryl and heterobiaryl scaffolds common in many therapeutic agents.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and polymers with specific electronic or structural properties.
• Chemical Biology & Diagnostics: Utilized in the synthesis of probes, tags, and molecular tools for biological research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Fluoro-4-Methylphenylboronic Acid
CAS No.	170981-26-7
Molecular Formula	C7H8BFO2
Molecular Weight	153.95 g/mol
Synonyms	(2-Fluoro-4-methylphenyl)boronic acid; 2-Fluoro-p-tolylboronic acid; 4-Methyl-2-fluorophenylboronic acid; Boronic acid, B-(2-fluoro-4-methylphenyl)-; 2-Fluoro-4-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of our 2-Fluoro-4-Methylphenylboronic Acid is produced and tested under stringent quality management systems. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible results in sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere for long-term stability, especially after opening the primary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.