Description

2-Iodo-Pivaloylaniline is a specialized halogenated aniline derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a pivaloyl-protected amine, makes it a versatile building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and functional polymers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive iodoarene moiety.
• Academic and R&D Laboratories: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Iodo-Pivaloylaniline
CAS No.	170959-10-1
Molecular Formula	C11H14INO
Molecular Weight	303.14 g/mol
Synonyms	N-(2-Iodophenyl)pivalamide; 2-Iodo-N-pivaloylaniline; Pivalanilide, 2'-iodo-; 2-Iodophenylpivalamide; 2-Iodo-benzenamine, N-(2,2-dimethyl-1-oxopropyl)-; 1-(2-Iodophenylamino)-2,2-dimethylpropan-1-one; Benzenamine, 2-iodo-N-(2,2-dimethyl-1-oxopropyl)-
EINECS	Contact for details

Quality Control

Our 2-Iodo-Pivaloylaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.