Description

tert-Butyl 4-(2-(2-Hydroxyethyl)Phenyl)Piperidine-1-Carboxylate is a sophisticated piperidine derivative and a key protected intermediate in modern organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and pesticides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial production of fine chemicals.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in catalytic systems.

Basic Information

Product Name	tert-Butyl 4-(2-(2-Hydroxyethyl)Phenyl)Piperidine-1-Carboxylate
CAS No.	170837-78-2
Molecular Formula	C18H27NO3
Molecular Weight	305.41 g/mol
Synonyms	1-Boc-4-[2-(2-hydroxyethyl)phenyl]piperidine; 1-(tert-Butoxycarbonyl)-4-[2-(2-hydroxyethyl)phenyl]piperidine; 4-[2-(2-Hydroxyethyl)phenyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[2-(2-hydroxyethyl)phenyl]-1-piperidinecarboxylate; 1-Boc-4-(2-(2-hydroxyethyl)phenyl)piperidine; 170837-78-2; 4-(2-(2-Hydroxyethyl)phenyl)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-(2-Hydroxyethyl)Phenyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.