Description

Des-5’-Chloro-4-Fluorobenzyl Mosapride is a key pharmaceutical intermediate and a derivative of the gastroprokinetic agent Mosapride. This compound is of significant value in the research and development of novel therapeutic agents targeting gastrointestinal motility disorders. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of Mosapride and its structural analogs for clinical development.
• Research Chemical: Used in academic and industrial research to study structure-activity relationships (SAR) of benzamide-based prokinetic agents.
• Process Development: Employed in the optimization of synthetic routes for the scalable production of gastrointestinal drugs.
• Reference Standard: Acts as a high-purity standard for analytical method development and quality control in API manufacturing.
• Preclinical Studies: Utilized in the development and evaluation of new chemical entities (NCEs) for potential therapeutic effects.

Basic Information

Product Name	Des-5’-Chloro-4-Fluorobenzyl Mosapride
CAS No.	170799-30-1
Molecular Formula	C21H24ClFN4O3
Molecular Weight	434.89 g/mol
Synonyms	4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide; Desbenzylmosapride; Mosapride Impurity; Mosapride Related Compound; 4-Amino-5-chloro-2-ethoxy-N-[(4-(4-fluorobenzyl)morpholin-2-yl)methyl]benzamide; UNII-9V7FGG8PZ1; 170799-30-1
EINECS	Contact for details

Quality Control

Our Des-5’-Chloro-4-Fluorobenzyl Mosapride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.