Description

(3α,5β)-7-Oxo-3α-Sulfato-5β-Cholan-24-Oate Disodium Salt is a high-purity, chemically modified bile acid derivative. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, particularly those targeting metabolic and liver-related pathways. It is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical sectors requiring precise molecular building blocks.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for novel therapeutic agents, including hepatoprotective drugs and modulators of nuclear receptors like FXR (Farnesoid X Receptor).
• Biochemical Research: Used as a reference standard and probe in metabolic pathway studies, enzyme inhibition assays, and bile acid metabolism research.
• Fine Chemical Synthesis: Serves as a versatile chiral template for the production of complex steroid-based molecules with high stereochemical purity.
• API Development: Employed in the development and scale-up of Active Pharmaceutical Ingredients (APIs) targeting cholestatic liver diseases and metabolic disorders.

Basic Information

Product Name	(3α,5β)-7-Oxo-3α-Sulfato-5β-Cholan-24-Oate Disodium Salt
CAS No.	170703-34-1
Molecular Formula	C24H36Na2O8S
Molecular Weight	538.58 g/mol
Synonyms	7-Oxo-3α-sulfolithocholic acid disodium salt; Disodium 3α-sulfo-7-oxo-5β-cholan-24-oate; Tauro-7-ketolithocholic acid sulfate disodium salt; 3α-Sulfate-7-oxolithocholate disodium; 7-Keto-LCA 3-sulfate disodium salt; 5β-Cholan-24-oic acid, 7-oxo-3α-sulfo-, sodium salt (1:2); 170703-34-1
EINECS	Contact for details

Quality Control

Our (3α,5β)-7-Oxo-3α-Sulfato-5β-Cholan-24-Oate Disodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.