Description

1H-Pyrrole-2-Carbonylfluoride,1-Methyl-5-(Trifluoromethyl)-(9Ci) is a specialized fluorinated pyrrole derivative, a high-value building block in advanced organic synthesis. Its core value lies in the strategic incorporation of both a reactive carbonyl fluoride group and a trifluoromethyl substituent, enabling precise molecular modifications that are difficult to achieve with other reagents. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where the introduction of fluorine atoms is critical for enhancing metabolic stability, bioavailability, and binding affinity. The CAS number for this compound is 170693-22-8.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially for incorporating fluorinated pyrrole motifs into potential therapeutics for oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the trifluoromethyl-pyrrole structure can contribute to improved efficacy and environmental profile.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials with tailored properties.
• Fluorination Chemistry: Employed as a specialized reagent for introducing fluorocarbonyl groups into complex molecules under controlled conditions.
• Chemical Biology & Proteomics: Utilized as a reactive handle for labeling or modifying biomolecules to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for fine chemical suppliers offering bespoke synthesis services for client-specific molecular targets.

Basic Information

Product Name	1H-Pyrrole-2-Carbonylfluoride,1-Methyl-5-(Trifluoromethyl)-(9Ci)
CAS No.	170693-22-8
Molecular Formula	C7H5F4NO
Molecular Weight	195.12 g/mol
Synonyms	1-Methyl-5-(trifluoromethyl)-1H-pyrrole-2-carbonyl fluoride; 1-Methyl-5-(trifluoromethyl)pyrrole-2-carbonyl fluoride; 2-(Fluoroformyl)-1-methyl-5-(trifluoromethyl)pyrrole; 1-Methyl-5-trifluoromethyl-1H-pyrrole-2-carboxylic acid fluoride; 1-Methyl-5-(trifluoromethyl)-2-pyrrolecarbonyl fluoride; 1-Methyl-5-(trifluoromethyl)pyrrole-2-carboxylic acid fluoride
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrole-2-Carbonylfluoride,1-Methyl-5-(Trifluoromethyl)-(9Ci) is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Standard analytical techniques including HPLC, GC, NMR, and IR spectroscopy are employed to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, ensure containers are kept tightly sealed to prevent moisture ingress and evaporation. Keep away from heat, sparks, open flames, and incompatible materials. Store under an inert atmosphere if specified for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.