Description

2-Chloro-N-(2,2,2-trifluoroethyl)acetamide is a specialized fluorinated acetamide derivative, a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring both chloroacetyl and trifluoroethyl groups, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring trifluoroethylamine or chloroacetamide pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms enhances biological activity and environmental stability.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the N-(2,2,2-trifluoroethyl)acetamide moiety into more complex molecular architectures.
• Material Science Research: Employed in the development of specialty polymers and functional materials that benefit from fluorine-containing segments.
• Chemical Research & Development: A valuable compound for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Chloro-N-(2,2,2-trifluoroethyl)acetamide
CAS No.	170655-44-4
Molecular Formula	C4H5ClF3NO
Molecular Weight	175.54 g/mol
Synonyms	2-Chloro-N-(2,2,2-trifluoroethyl)acetamide; Acetamide, 2-chloro-N-(2,2,2-trifluoroethyl)-; N-(2,2,2-Trifluoroethyl)-2-chloroacetamide; 2-Chloro-2',2',2'-trifluoroacetamilide; α-Chloro-N-(2,2,2-trifluoroethyl)acetamide; Chloro(trifluoroethyl)acetamide; TFEA-CA
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-N-(2,2,2-trifluoroethyl)acetamide is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.