Description

4-Chloro-2,6-Difluorophenyl Methyl Ether, also known as 5-Chloro-1,3-Difluoro-2-Methoxybenzene, is a high-purity halogenated aromatic ether building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for display technologies, contributing to improved performance characteristics.
• Organic Electronic Materials: Acts as a precursor in the synthesis of specialized monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new reactions in cross-coupling and nucleophilic aromatic substitution chemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments that offer enhanced lightfastness and color properties.

Basic Information

Product Name	4-Chloro-2,6-Difluorophenyl Methyl Ether / 5-Chloro-1,3-Difluoro-2-Methoxybenzene
CAS No.	170572-51-7
Molecular Formula	C7H5ClF2O
Molecular Weight	178.56 g/mol
Synonyms	1-Chloro-3,5-difluoro-2-methoxybenzene; 2-Methoxy-3,5-difluorochlorobenzene; Methyl 4-chloro-2,6-difluorophenyl ether; 5-Chloro-1,3-difluoro-2-methoxybenzene; 4-Chloro-2,6-difluoroanisole; 2-Chloro-4,6-difluoroanisole (isomer check); Benzene, 1-chloro-3,5-difluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,6-Difluorophenyl Methyl Ether is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Ensure the container is kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.