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6-(Diaminomethylideneamino)Hexylcarbamoylmethyl n-[4-[[(3R)-3-Aminobutyl]Amino]Butyl]Carbamate CAS NO 170368-04-4


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CAS No.:170368-04-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(Diaminomethylideneamino)Hexylcarbamoylmethyl n-[4-[[(3R)-3-Aminobutyl]Amino]Butyl]Carbamate is a high-purity, synthetic chemical building block featuring multiple reactive amino and carbamate functional groups. This compound is valued for its role as a versatile linker or spacer molecule in advanced pharmaceutical and bioconjugation research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and life science sectors for the synthesis of targeted drug conjugates, prodrugs, and complex molecular constructs.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for cancer therapeutics and targeted drug delivery systems.
  • Bioconjugation & Linker Chemistry: Used to covalently attach drugs, dyes, or other functional molecules to antibodies, proteins, or nanoparticles, enabling the creation of antibody-drug conjugates (ADCs) and diagnostic probes.
  • Prodrug Synthesis: Employed in the design and development of prodrugs, where its structure can be utilized to improve drug solubility, stability, or targeted release profiles.
  • Peptide Mimetics & Modification: Acts as a spacer or functional handle for the modification of peptides and peptide analogs to enhance their pharmacological properties.
  • Polymer & Material Science: Can be incorporated into specialty polymers and hydrogels as a cross-linking agent or to introduce bioactive sites for biomedical applications.
  • Research & Development: Essential tool compound in academic and industrial research laboratories for exploring new chemical entities and bioconjugation strategies.

Basic Information

Product Name 6-(Diaminomethylideneamino)Hexylcarbamoylmethyl n-[4-[[(3R)-3-Aminobutyl]Amino]Butyl]Carbamate
CAS No. 170368-04-4
Molecular Formula C19H40N8O4
Molecular Weight 444.58 g/mol
Synonyms N-[6-[(Diaminomethylidene)amino]hexyl]-2-[[4-[[(3R)-3-aminobutyl]amino]butyl]amino]-2-oxoacetamide; 6-Guanidinohexyl N-[4-[[(3R)-3-Aminobutyl]amino]butyl]oxamamate; (3R)-N1-[4-[[2-[(6-Guanidinohexyl)amino]-2-oxoacetyl]amino]butyl]butane-1,3-diamine; Oxamic acid derivative linker; ADC linker precursor; Guanidinohexyl-oxamamate-aminobutylamine
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Quality Control

Our 6-(Diaminomethylideneamino)Hexylcarbamoylmethyl n-[4-[[(3R)-3-Aminobutyl]Amino]Butyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Chiral Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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