Description

[4-(2,2,2-Trifluoroethoxy)Phenyl]Acetic Acid is a high-value fluorinated aromatic building block, essential for synthesizing advanced pharmaceutical intermediates and agrochemicals. Its unique trifluoroethoxy side chain imparts desirable metabolic stability and lipophilicity to target molecules, making it a critical component in modern drug discovery and specialty chemical development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to incorporate fluorine chemistry into their products.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for developing next-generation herbicides and fungicides with enhanced efficacy and environmental profile.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronics: Serves as a monomer or dopant in the development of organic semiconductors and electro-optical materials.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring fluorinated aromatic compounds and their properties.
• Peptide Mimetics: Incorporated into peptide analogs to improve bioavailability and metabolic resistance.

Basic Information

Product Name	[4-(2,2,2-Trifluoroethoxy)Phenyl]Acetic Acid
CAS No.	170361-35-0
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	2-[4-(2,2,2-Trifluoroethoxy)phenyl]acetic acid; 4-(2,2,2-Trifluoroethoxyphenyl)acetic acid; p-(Trifluoroethoxy)phenylacetic acid; 2-(4-(Trifluoroethoxy)phenyl)acetic acid; 170361-35-0; Acetic acid, 2-[4-(2,2,2-trifluoroethoxy)phenyl]-; (4-Trifluoroethoxyphenyl)acetic acid
EINECS	Contact for details

Quality Control

Our [4-(2,2,2-Trifluoroethoxy)Phenyl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.