Description

(S)-tert-Butyl 3-Carbamoylpiperazine-1-Carboxylate is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• API Development: Used in constructing the core scaffold of potential Active Pharmaceutical Ingredients (APIs) requiring a specific (S)-configuration.
• Peptidomimetics & PROTACs: Serves as a crucial component in the design of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) for targeted protein degradation.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme function and biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in asymmetric catalytic reactions to induce stereoselectivity.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to pharmaceutical and biotech clients.

Basic Information

Product Name	(S)-tert-Butyl 3-Carbamoylpiperazine-1-Carboxylate
CAS No.	170164-47-3
Molecular Formula	C10H19N3O3
Molecular Weight	229.28 g/mol
Synonyms	1-Boc-3-carbamoyl-(S)-piperazine; (S)-1-(tert-Butoxycarbonyl)-3-carbamoylpiperazine; tert-Butyl (3S)-3-carbamoylpiperazine-1-carboxylate; (S)-1-Boc-3-aminocarbonylpiperazine; (S)-3-Carbamoyl-1-N-Boc-piperazine; (S)-N-Boc-3-piperazinecarboxamide; (S)-1-N-Boc-3-piperazinecarboxamide; (3S)-1-(tert-Butoxycarbonyl)piperazine-3-carboxamide
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-Carbamoylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.