Description

(S,S)-(+)-Pseudoephedrine Glycinamide is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in the central nervous system and respiratory therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to ensure precise stereochemical control and high yield in complex synthetic pathways, directly impacting the efficacy and safety profile of the final drug product.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure pharmaceuticals, including potential decongestants and bronchodilators.
• Asymmetric Synthesis: Used in research and development for constructing complex molecules with defined stereochemistry, leveraging its rigid pseudoephedrine backbone.
• Medicinal Chemistry Research: Serves as a valuable scaffold or precursor in the discovery and optimization of new chemical entities targeting adrenergic receptors.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related drug substances.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Chemical Biology Probes: Can be functionalized to create molecular tools for studying biological pathways and protein interactions.

Basic Information

Product Name	(S,S)-(+)-Pseudoephedrine Glycinamide
CAS No.	170115-96-5
Molecular Formula	C11H17N3O
Molecular Weight	207.27 g/mol
Synonyms	(1S,2S)-2-(Methylamino)-1-phenyl-1-propanol glycinamide; (1S,2S)-N-(2-Amino-2-oxoethyl)-N-methylpseudoephedrine; (+)-(1S,2S)-Pseudoephedrine Glycinamide; Pseudoephedrine Glycinamide; (S,S)-Pseudoephedrine Glycinamide; SS-Pseudoephedrine Glycinamide; (1S,2S)-Pseudoephedrine-2-carboxamide
EINECS	Contact for details

Quality Control

Our (S,S)-(+)-Pseudoephedrine Glycinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.