Description

Alvimopan Metabolite (Adl08-0011),Hydrochloride Salt is a key pharmaceutical reference standard and synthetic intermediate. This compound is critical for research and development in pharmacology, particularly for studies related to drug metabolism and pharmacokinetics (DMPK). It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in advanced drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Alvimopan and its metabolites in biological matrices via HPLC, LC-MS, and other analytical techniques.
• Drug Metabolism Studies: Essential for investigating the metabolic pathways, bioavailability, and excretion profiles of Alvimopan in preclinical and clinical research.
• Analytical Method Development & Validation: Serves as a critical component in developing, calibrating, and validating robust bioanalytical assays for regulatory submissions.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Research: Employed in studies to understand the relationship between drug concentration and physiological effect for gastrointestinal recovery agents.
• Impurity Profiling & Characterization: Used to identify, quantify, and monitor process-related impurities and degradation products in active pharmaceutical ingredient (API) batches.
• Synthetic Intermediate: Can be utilized in the chemical synthesis of novel compounds or derivatives for further pharmacological evaluation.

Basic Information

Product Name	Alvimopan Metabolite (Adl08-0011),Hydrochloride Salt
CAS No.	170098-43-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ADL 08-0011; ADL08-0011; Alvimopan Metabolite Hydrochloride; (2S)-2-[[(2S)-2-[[4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]amino]acetic acid hydrochloride; ADL-08-0011; UNII-7B3U6QDK6Q; 7B3U6QDK6Q; Alvimopan metabolite ADL 08-0011 HCl
EINECS	Contact for details

Quality Control

Our Alvimopan Metabolite (Adl08-0011),Hydrochloride Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR, MS) and purity assessment by HPLC to ensure it meets the stringent requirements for research and reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific results for identity, purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.