Description

3,5-Bis(Methylsulfonyl)Benzonitrile is a high-purity, multi-functional organic building block characterized by its unique benzonitrile core flanked by two methylsulfonyl groups. This compound matters for its role as a critical intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where its electron-withdrawing sulfonyl groups and nitrile functionality enable precise molecular modifications. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules, including potential active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring a disubstituted aromatic core.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where its structural motifs contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and liquid crystals due to its polar and rigid structure.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	3,5-Bis(Methylsulfonyl)Benzonitrile
CAS No.	169696-83-7
Molecular Formula	C9H9NO4S2
Molecular Weight	259.30 g/mol
Synonyms	3,5-Bis(methanesulfonyl)benzonitrile; 3,5-Dimethanesulfonylbenzonitrile; Benzonitrile, 3,5-bis(methylsulfonyl)-; 3,5-Bis(methylsulphonyl)benzonitrile; 1-Cyano-3,5-bis(methylsulfonyl)benzene; 3,5-Dimethylsulfonylbenzonitrile; 3,5-Bis(mesyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Methylsulfonyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.