Description

(1S,2S)-(-)-1,2-Diaminocyclohexane-N,N'-Bis(2'-Diphenylphosphinobenzoyl) is a highly specialized chiral ligand, pivotal for creating asymmetric catalytic systems. Its value lies in enabling precise stereochemical control in critical synthetic transformations, directly impacting yield and enantiomeric purity. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-performance catalysts for complex molecule synthesis.

Application

• Asymmetric Hydrogenation Catalysis: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing chiral intermediates in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer drug candidates and chiral building blocks with high optical purity.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides where biological activity is stereospecific.
• Fine Chemical Production: Facilitates asymmetric carbon-carbon and carbon-heteroatom bond-forming reactions for high-value specialty chemicals.
• Academic & Industrial R&D: Serves as a fundamental tool for developing new catalytic methodologies and exploring novel reaction pathways in organic synthesis.
• Catalyst Screening Libraries: A critical component in high-throughput screening for identifying optimal catalyst systems for specific asymmetric transformations.

Basic Information

Product Name	(1S,2S)-(-)-1,2-Diaminocyclohexane-N,N'-Bis(2'-Diphenylphosphinobenzoyl)
CAS No.	169689-05-8
Molecular Formula	C46H42N2O2P2
Molecular Weight	716.79 g/mol
Synonyms	(1S,2S)-(-)-1,2-DACH-Bis(Diphenylphosphinobenzoyl); (S,S)-DACH-BDPB; (1S,2S)-DACH-BDPB Ligand; (S,S)-1,2-Diaminocyclohexane-N,N'-bis(2-diphenylphosphinobenzoyl); (S,S)-Cyclohexanediamine-N,N'-bis(2-(diphenylphosphino)benzoyl); Chiral DACH-DPPB Ligand; (S,S)-DACH-(DPPB)2; Asymmetric Hydrogenation Ligand 169689-05-8
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands is produced and tested under strict quality management to ensure consistent high performance in catalytic applications. We guarantee high chiral purity and chemical integrity, with specifications typically covering identity, assay, enantiomeric excess (e.e.), and residual solvent content. A comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and optical rotation analysis is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (e.e.)	≥ 99.0%
Specific Rotation [α]D20	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.