Description

Methyl 3-Amino-4,4,4-Trifluorobutyrate Hydrochloride is a high-value trifluoromethylated building block essential for modern synthetic chemistry. This compound is a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is critical for enhancing metabolic stability and bioavailability. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the trifluoromethyl group imparts improved activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty monomers and polymers with unique surface properties and chemical resistance.
• Peptide Mimetics: Employed in the construction of fluorinated amino acid analogs for peptide-based therapeutics and diagnostic tools.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise fluorination.

Basic Information

Product Name	Methyl 3-Amino-4,4,4-Trifluorobutyrate Hydrochloride
CAS No.	169605-23-6
Molecular Formula	C5H9F3NO2·HCl
Molecular Weight	223.59 g/mol
Synonyms	3-Amino-4,4,4-trifluorobutanoic acid methyl ester hydrochloride; Methyl 3-amino-4,4,4-trifluorobutanoate hydrochloride; 4,4,4-Trifluoro-3-aminobutanoic acid methyl ester hydrochloride; 3-Amino-4,4,4-trifluorobutyric acid methyl ester HCl; Methyl β-amino-γ,γ,γ-trifluorobutyrate hydrochloride; MFAB hydrochloride; 169605-23-6
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-4,4,4-Trifluorobutyrate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.