Description

L-Methionine, n-[1-[[(1,1-Dimethylethyl)Amino]Carbonyl]-2-Methylpropyl]-, Methyl Ester, (R)- (9Ci) is a specialized, optically active methionine derivative designed for advanced chemical synthesis. This compound serves as a high-purity chiral building block, crucial for introducing specific stereochemistry and functional groups into target molecules. It is primarily required by pharmaceutical research and fine chemical industries for the development of novel active ingredients and complex organic intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in peptide mimetics and enzyme inhibitors.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics where the tert-butyloxycarbonyl (Boc) protected amine and methyl ester functionalities are advantageous.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Biochemical Research: Utilized in studies involving amino acid metabolism, protein engineering, and as a standard for analytical method development.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialized agrochemicals, advanced materials, and custom-designed ligands for catalysis.

Basic Information

Item	Detail
Product Name	L-Methionine, n-[1-[[(1,1-Dimethylethyl)Amino]Carbonyl]-2-Methylpropyl]-, Methyl Ester, (R)- (9Ci)
CAS No.	169453-35-4
Molecular Formula	C11H22N2O3S
Molecular Weight	262.37 g/mol
Synonyms	Boc-L-methionine methyl ester; (R)-Methyl 2-((tert-butoxycarbonyl)amino)-4-(methylthio)butanoate; N-Boc-L-methionine methyl ester; Boc-Met-OMe; N-(tert-Butoxycarbonyl)-L-methionine methyl ester; L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Methyl N-Boc-L-methioninate
EINECS	Contact for details

Quality Control

We supply this high-value intermediate under a strict quality management system. Each batch is characterized and tested to ensure identity, purity, and chiral integrity, with specifications typically covering assay (HPLC), enantiomeric excess, and related substances. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all test results against agreed specifications. Our production adheres to cGMP principles where required, ensuring reliable batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.