Description

Glycine, n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]-n-[[6-[[(Phenylmethoxy)Carbonyl]Amino]-9H-Purin-9-Yl]Acetyl]- is a sophisticated, multi-functional protected amino acid derivative designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity, structurally complex building blocks for peptide and nucleoside analog development. It is primarily utilized in pharmaceutical R&D, particularly in the synthesis of oligonucleotides, modified peptides, and other bioactive molecules where precise molecular architecture is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected amino acid building block for introducing specific functional groups into peptide chains.
• Oligonucleotide Synthesis: Used in the preparation of nucleoside-amino acid conjugates and other modified nucleic acid constructs for therapeutic and diagnostic applications.
• Pharmaceutical Intermediate: Acts as a crucial intermediate in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting genetic diseases.
• Bioconjugation Chemistry: Facilitates the site-specific labeling and cross-linking of biomolecules (proteins, nucleic acids) for probe and drug delivery system development.
• Combinatorial Chemistry Libraries: Employed to create diverse libraries of compounds for high-throughput screening in drug discovery programs.
• Academic and Industrial Research: Provides a versatile tool for synthetic chemists exploring new molecular entities and reaction pathways in medicinal chemistry.

Basic Information

Product Name	Glycine, n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]-n-[[6-[[(Phenylmethoxy)Carbonyl]Amino]-9H-Purin-9-Yl]Acetyl]-
CAS No.	169396-98-9
Molecular Formula	C33H31N7O7
Molecular Weight	637.65 g/mol
Synonyms	Fmoc-Glycine-EDA-N6-Cbz-Adenine Acetic Acid; N-((6-((Benzyloxy)carbonyl)amino)-9H-purin-9-yl)acetyl)-N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)glycine; N6-Cbz-Adenine-Fmoc-Gly-EDA; Glycine, N-(2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)ethyl)-N-((6-(((phenylmethoxy)carbonyl)amino)-9H-purin-9-yl)acetyl)-; Fmoc-Gly-EDA-N6-Cbz-Ade-OH; Adenine(Cbz)-Gly(Fmoc)-EDA Building Block
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your critical research and cGMP-aligned development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Under these conditions, the product is stable for at least 24 months from the date of receipt. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.