Description

Glycine, n-[2-(3,4-Dihydro-5-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Acetyl]-n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]- is a sophisticated, high-purity chemical building block designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular control in the development of novel active ingredients. It is primarily utilized in the pharmaceutical and biotechnology sectors for applications such as peptide synthesis and the creation of nucleotide analogs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting viral or genetic diseases.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a specialized, protected amino acid derivative for constructing complex peptide sequences.
• Nucleotide Analog Development: Serves as a precursor or modified component in the research and production of nucleotide analogs for therapeutic applications.
• Bioconjugation: Facilitates the site-specific labeling or conjugation of biomolecules (e.g., proteins, oligonucleotides) for diagnostic or therapeutic purposes.
• Protecting Group Chemistry: The Fmoc (9-fluorenylmethoxycarbonyl) protecting group is integral for temporary amine protection in multi-step organic syntheses.
• Research & Development: An essential reagent in academic and industrial R&D labs for exploring new chemical entities and biochemical pathways.

Basic Information

Product Name	Glycine, n-[2-(3,4-Dihydro-5-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Acetyl]-n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]-
CAS No.	169396-92-3
Molecular Formula	C26H26N4O6
Molecular Weight	490.51 g/mol
Synonyms	Fmoc-Gly-Thymine acetic acid derivative; N-((9H-Fluoren-9-ylmethoxy)carbonyl)-N'-(2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetyl)ethylenediamine; N-Fmoc-N'-(thymin-1-ylacetyl)ethylenediamine; Thymine-1-acetic acid, N-Fmoc-ethylenediamine derivative; Glycine, N-[2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; Fmoc-Gly-Thy-OH derivative; 1-(Carboxymethyl)thymine Fmoc-ethylenediamine amide
EINECS	Contact for details

Quality Control

Our Glycine, n-[2-(3,4-Dihydro-5-Methyl-2,4-Dioxo-1(2H)-Pyrimidinyl)Acetyl]-n-[2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]Ethyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.