Description

Boc-Pna-G(Z)-Oh CAS NO 169287-77-8 is a protected amino acid derivative, specifically a Boc-protected peptide building block. This compound is essential for the controlled synthesis of complex peptides and peptidomimetics in solid-phase and solution-phase chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, proteomics research, and the development of therapeutic peptides.

Application

• Pharmaceutical Intermediates: Critical building block for the synthesis of novel peptide-based active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase peptide synthesis (SPPS) and solution-phase methods to construct specific peptide sequences.
• Drug Discovery & Research: Serves as a key reagent in medicinal chemistry for creating libraries of peptide analogs for biological screening.
• Bioconjugation: Can be utilized in the preparation of peptide-protein conjugates or peptide-labeled compounds for diagnostic and research applications.
• Proteomics & Biochemical Tools: Employed in the synthesis of substrate analogs, enzyme inhibitors, and probes for studying protein function.

Basic Information

Product Name	Boc-Pna-G(Z)-Oh
CAS No.	169287-77-8
Molecular Formula	C₂₀H₂₈N₂O₇
Molecular Weight	408.45 g/mol
Synonyms	Boc-Pna-G(Z)-OH; N-α-(tert-Butoxycarbonyl)-N-ω-(benzyloxycarbonyl)-L-2,4-diaminobutanoic Acid; Boc-Dab(Z)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic Acid (related Fmoc variant); Nα-Boc-Nω-Z-L-2,4-diaminobutyric Acid; Boc-L-Dab(Z)-OH; L-2,4-Diaminobutyric Acid Nα-Boc, Nω-Z derivative; Boc-Dab(Z)-OH peptide building block.
EINECS	Contact for details

Quality Control

Our Boc-Pna-G(Z)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.