Description

G(Cbz)-Acetic Acid CAS NO 169287-69-8 is a high-purity, protected amino acid derivative widely used as a critical building block in organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular construction, particularly in the development of complex peptides and pharmaceutical intermediates. It is primarily utilized by the pharmaceutical, biotechnology, and advanced chemical synthesis industries for applications demanding high fidelity and reliable supply.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Serves as a protected glycine derivative for solid-phase and solution-phase peptide coupling, enabling the construction of specific peptide sequences.
• Bioconjugation: Used in the modification of biomolecules, such as proteins and antibodies, for drug delivery systems and diagnostic applications.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating specialized molecular libraries.
• Protecting Group Chemistry: The Cbz (carboxybenzyl) group provides amine protection, making this acid crucial for multi-step syntheses where selective deprotection is required.

Basic Information

Product Name	G(Cbz)-Acetic Acid
CAS No.	169287-69-8
Molecular Formula	C11H13NO4
Molecular Weight	223.23 g/mol
Synonyms	N-Carbobenzoxyglycine; N-Cbz-Glycine; (Carbobenzyloxyamino)acetic Acid; Z-Gly-OH; Glycine, N-[(phenylmethoxy)carbonyl]-; NSC 3349; Benzyloxycarbonylglycine; N-(Benzyloxycarbonyl)glycine
EINECS	Contact for details

Quality Control

Our G(Cbz)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.