Description

2-(Benzyloxy)-5-Bromo-1-Trifluoromethylbenzene is a high-purity, multi-functional aromatic building block featuring bromine and trifluoromethyl substituents, making it a valuable intermediate for advanced synthesis. Its molecular structure is engineered to facilitate selective coupling reactions and serve as a precursor for complex, functionalized molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the trifluoromethyl group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromine atom allows for further functionalization to create targeted bioactive molecules.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique electronic or optical properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Fluorine Chemistry: The stable trifluoromethyl group is utilized to study the effects of fluorination on material properties and biological activity.

Basic Information

Item	Details
Product Name	2-(Benzyloxy)-5-Bromo-1-Trifluoromethylbenzene
CAS No.	169247-46-5
Molecular Formula	C14H10BrF3O
Molecular Weight	331.13 g/mol
Synonyms	5-Bromo-2-(benzyloxy)-1-(trifluoromethyl)benzene; 1-Benzyloxy-4-bromo-2-trifluoromethylbenzene; 2-Benzyloxy-5-bromo-alpha,alpha,α-trifluorotoluene; 5-Bromo-2-(phenylmethoxy)-1-(trifluoromethyl)benzene; 2-(Benzyloxy)-5-bromo-1-(trifluoromethyl)benzene; 2-Benzyloxy-5-bromobenzotrifluoride; 169247-46-5; 5-Bromo-2-benzyloxybenzotrifluoride
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzyloxy)-5-Bromo-1-Trifluoromethylbenzene is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.