Description

(3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)Methanol is a versatile fluorinated pyrazole derivative, a high-value building block prized for its unique trifluoromethyl group which imparts desirable properties like enhanced metabolic stability and lipophilicity to final compounds. This compound is essential for research and development chemists focused on creating novel active molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors, antiviral agents, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors used in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)Methanol
CAS No.	169213-73-4
Molecular Formula	C5H5F3N2O
Molecular Weight	166.10 g/mol
Synonyms	5-(Hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazole; 3-(Trifluoromethyl)-1H-pyrazole-5-methanol; 1H-Pyrazole-5-methanol, 3-(trifluoromethyl)-; (3-Trifluoromethyl-1H-pyrazol-5-yl)methanol; 5-(Hydroxymethyl)-3-(trifluoromethyl)pyrazole
EINECS	Contact for details

Quality Control

Our (3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and GC-MS are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.