Description

Sac7 Protein CAS NO 169149-38-6 is a small, highly stable DNA-binding protein derived from the hyperthermophilic archaeon *Sulfolobus acidocaldarius*. This unique protein matters for its exceptional thermostability and ability to bind and condense DNA without sequence specificity, making it a valuable tool in molecular biology and nanotechnology. It is primarily needed by researchers and manufacturers in the fields of biochemical research, structural biology, and the development of novel biomaterials and nano-assemblies.

Application

• Molecular Biology Research: Used as a model protein for studying protein-DNA interactions, protein folding, and stability under extreme conditions.
• DNA Condensation & Nanostructure Assembly: Employed to compact DNA for studies in gene delivery, nanoparticle formation, and the construction of defined nanoarchitectures.
• Structural Studies: Ideal for X-ray crystallography and NMR spectroscopy due to its small size, stability, and well-defined DNA-binding properties.
• Enzyme Stabilization: Can be utilized as a fusion partner or additive to enhance the thermal stability of other enzymes in biocatalysis.
• Biomaterial Development: Investigated for creating novel bio-inspired materials, coatings, and sensors that leverage its robust physical properties.
• Diagnostic Reagent Component: Potential use in diagnostic kits where stable protein-DNA complexes are required.

Basic Information

Product Name	Sac7 Protein
CAS No.	169149-38-6
Molecular Formula	C292H457N83O86S
Molecular Weight	~6.8 kDa
Synonyms	Sac7d; DNA-binding protein 7d; Sso7d; Sulfolobus acidocaldarius DNA-binding protein 7; Archaeal chromatin protein; Hyperthermostable DNA-binding protein; Sso DNA-binding protein 7; SSO7D; Sso7d protein; Sso7d Sac7d; Thermophilic DNA-binding protein.
EINECS	Contact for details

Quality Control

Our Sac7 Protein is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and functional DNA-binding assays. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly in a dry environment after each use.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95%
Protein Content (UV)	≥ 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
DNA-Binding Activity (Gel Shift)	Active
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.