Description

Human HCC-1 is a synthetic peptide belonging to the chemokine family, specifically a variant of the CCL14 protein. This compound is a critical research-grade biochemical used to study inflammatory processes, immune cell recruitment, and specific receptor interactions. It is essential for researchers and developers in the fields of immunology, oncology, and drug discovery who require high-purity, well-characterized bioactive peptides.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of chemokine biology, inflammation, and immune system signaling pathways.
• Drug Discovery & Development: Serves as a key reagent in high-throughput screening assays to identify potential inhibitors or modulators of chemokine receptor activity.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate its effects on leukocyte migration, activation, and proliferation.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (e.g., ELISA) for detecting chemokine levels in biological samples.
• Receptor Binding Studies: Essential for characterizing binding affinity and specificity to target receptors such as CCR1 and CCR3 in pharmacological research.

Basic Information

Product Name	Human HCC-1
CAS No.	169146-44-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CCL14; C-C motif chemokine 14; HCC-1; NCC-2; CC chemokine ligand 14; CKb1; MCIF; Small-inducible cytokine A14; SCYA14
EINECS	Contact for details

Quality Control

Our Human HCC-1 is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry for identity confirmation, and bioactivity assays to verify functional performance. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Aliquot to avoid repeated freeze-thaw cycles. Under these conditions, the product is stable for at least two years from the date of receipt.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Determined by cell migration or receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.