Description

3-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated aromatic building block characterized by its cinnamic acid core and trifluoromethoxy substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of advanced electronic materials for displays and lighting due to its aromatic and fluorinated structure.
• Organic Synthesis & Chemical Research: A versatile reagent for introducing the 3-(trifluoromethoxy)phenyl moiety into more complex molecular architectures in academic and industrial R&D.
• Fluorinated Polymer Modifiers: Can be utilized to synthesize monomers that impart special properties like chemical resistance and low surface energy to polymers.

Basic Information

Product Name	3-(Trifluoromethoxy)Cinnamic Acid
CAS No.	168833-80-5
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	(E)-3-[3-(Trifluoromethoxy)phenyl]acrylic acid; 3-(Trifluoromethoxy)benzeneacrylic acid; trans-3-(3-Trifluoromethoxyphenyl)acrylic Acid; (E)-3-(3-(Trifluoromethoxy)phenyl)prop-2-enoic acid; α,3-Bis(trifluoromethoxy)cinnamic acid (incorrect but common search variant); 3-Trifluoromethoxycinnamate; TFMCA
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethoxy)Cinnamic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.