Description

n-[(4-Chlorophenyl)(4-Fluorophenyl)Methyl]Acetamide is a specialized organic compound featuring a diphenylmethyl core structure substituted with chloro and fluoro groups, capped with an acetamide moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for fine chemical synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Serves as a precursor for novel pesticides, herbicides, or fungicides, leveraging the bioactivity of its halogenated aromatic system.
• Organic Light-Emitting Diode (OLED) Materials: Potential use as a core or dopant material in the development of electron-transport or host layers for display technologies.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel chiral ligands or catalysts for asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to impart specific properties like flame retardancy or UV stability to advanced polymers.
• Academic and Industrial Research: A valuable reference standard and starting material for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	n-[(4-Chlorophenyl)(4-Fluorophenyl)Methyl]Acetamide
CAS No.	168779-39-3
Molecular Formula	C15H13ClFNO
Molecular Weight	277.72 g/mol
Synonyms	N-[(4-Chlorophenyl)(4-fluorophenyl)methyl]acetamide; 1-[(4-Chlorophenyl)(4-fluorophenyl)methyl]acetamide; N-[(p-Chlorophenyl)(p-fluorophenyl)methyl]acetamide; N-(Bis(4-chlorophenyl)(4-fluorophenyl)methyl)acetamide (common misnomer); Acetamide, N-[(4-chlorophenyl)(4-fluorophenyl)methyl]-; (4-Chloro-4'-fluorodiphenylmethyl)acetamide; α-Acetamido-4-chloro-4'-fluorodiphenylmethane
EINECS	Contact for details

Quality Control

Our n-[(4-Chlorophenyl)(4-Fluorophenyl)Methyl]Acetamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and structural identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.