Description

2-Bromo-n-(tert-Butyl)Benzamide is a high-purity, specialized organic intermediate featuring a brominated aromatic ring and a sterically hindered tert-butyl amide group. This compound matters for its role as a critical building block in advanced organic synthesis, enabling the introduction of both bromine and a bulky amide moiety in a single step. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry for lead optimization and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that require halogenated aromatic structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, or polymers where bromine atoms facilitate further cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for fine chemical manufacturers offering bespoke synthesis services for client-specific molecular targets.
• Academic and R&D Laboratories: Used in fundamental research to study reaction mechanisms, steric effects, and to create compound libraries for biological screening.

Basic Information

Item	Detail
Product Name	2-Bromo-n-(tert-Butyl)Benzamide
CAS No.	168265-57-4
Molecular Formula	C11H14BrNO
Molecular Weight	256.14 g/mol
Synonyms	2-Bromo-N-(tert-butyl)benzamide; N-(tert-Butyl)-2-bromobenzamide; 2-Bromo-N-(1,1-dimethylethyl)benzamide; Benzamide, 2-bromo-N-(1,1-dimethylethyl)-; 2-Bromobenzoic acid tert-butylamide; t-Butyl 2-bromobenzamide; 168265-57-4; AI3-52300
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-n-(tert-Butyl)Benzamide is produced and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your precise research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.