Description

1-Propanone, 2,2,3,3-Tetrafluoro-1-(4-Methylphenyl)- (9Ci) is a specialized fluorinated aromatic ketone, a high-value building block prized for its unique chemical reactivity and stability profile. This compound is critical for advanced organic synthesis, particularly in the development of novel materials and active pharmaceutical ingredients (APIs) where the introduction of fluorine atoms is desired. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to enhance the properties of their end products.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing fluorinated drug candidates, potentially improving metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination can increase efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Material Modifier: Incorporated into polymer chains to impart specific characteristics such as chemical resistance, thermal stability, or altered surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex fluorinated molecular architectures via reactions like Friedel-Crafts acylation or nucleophilic addition.
• Fluorinated Surfactant & Coating Precursor: Acts as a starting material for creating surface-active agents and high-performance coatings with low surface energy.

Basic Information

Product Name	1-Propanone, 2,2,3,3-Tetrafluoro-1-(4-Methylphenyl)- (9Ci)
CAS No.	168167-73-5
Molecular Formula	C10H8F4O
Molecular Weight	220.17 g/mol
Synonyms	2,2,3,3-Tetrafluoro-1-(4-methylphenyl)propan-1-one; 4-Methyl-2,2,3,3-tetrafluoropropiophenone; p-Methyl-α,α,β,β-tetrafluoropropiophenone; 1-(4-Methylphenyl)-2,2,3,3-tetrafluoropropan-1-one; 4-Methyl-α,α,β,β-tetrafluoropropiophenone; 1-Propanone, 2,2,3,3-tetrafluoro-1-(4-methylphenyl)-; Tetrafluoro(4-methylphenyl)propanone
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 2,2,3,3-Tetrafluoro-1-(4-Methylphenyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical specifications. Our quality system is designed to support applications requiring high-purity intermediates under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.