Description

Stat6 Protein CAS NO 168115-60-4 is a high-purity recombinant protein, specifically the Signal Transducer and Activator of Transcription 6, which plays a critical role in the IL-4 and IL-13 signaling pathways. This protein is essential for fundamental life science research, enabling the study of immune responses, allergic reactions, and cellular signaling mechanisms. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and academic sectors for applications such as assay development, target validation, and biochemical studies.

Application

• Biochemical Research: Used as a key reagent in studying JAK-STAT signaling pathways, particularly those mediated by IL-4 and IL-13.
• Drug Discovery & Target Validation: Serves as a critical target protein for screening and developing novel therapeutics for immune disorders, asthma, and allergies.
• Assay Development: Employed in the development of ELISA, Western Blot, and other immunoassays to detect and quantify STAT6 activity or interactions.
• Cell Signaling Studies: Utilized in vitro to investigate the mechanisms of cytokine-mediated gene expression and cellular differentiation.
• Protein-Protein Interaction Analysis: Acts as a bait or prey protein in pull-down assays, co-immunoprecipitation, and surface plasmon resonance (SPR) studies.
• Antibody Production & Specificity Testing: Used as a pure antigen for generating and characterizing monoclonal or polyclonal antibodies.

Basic Information

Item	Detail
Product Name	Stat6 Protein
CAS No.	168115-60-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	STAT6; Signal Transducer and Activator of Transcription 6; IL-4 Stat; Transcription Factor STAT6; STAT6 Protein, Human; Recombinant STAT6; STAT6 Recombinant Protein; STAT6 (Signal Transducer and Activator of Transcription 6)
EINECS	Contact for details

Quality Control

Our Stat6 Protein is produced under stringent conditions and undergoes rigorous analytical testing to ensure high purity, identity, and biological activity. Each batch is tested for purity by SDS-PAGE and HPLC, with identity confirmed by mass spectrometry. The product is free from detectable endotoxins and proteases. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (Mass Spec)	Conforms
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Biological Activity	Assessed by functional assay (e.g., DNA-binding ELISA)
Endotoxin Level	< 1.0 EU/µg
Protein Concentration	Verified by UV absorbance
Buffer Composition	Specified in COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.