Description

2-C-(2,3,4,6-Tetra-O-Acetyl-β-D-Glucopyranosyl) Ethyne is a key protected glycosyl donor and a versatile synthetic intermediate in carbohydrate and medicinal chemistry. This compound is essential for constructing complex glycoconjugates and nucleoside analogs through efficient glycosylation and click chemistry reactions. It is primarily required by pharmaceutical R&D laboratories, agrochemical developers, and academic research institutions focused on drug discovery and chemical biology.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (click reactions) for bioconjugation and material labeling.
• Carbohydrate Chemistry Research: Serves as a protected glycosyl donor for stereoselective glycosylation reactions in academic and industrial research.
• Agrochemical Development: Used in the synthesis of novel, bioactive carbohydrate-based compounds for crop protection.
• Chemical Probe Development: Enables the creation of molecular probes for studying glycosylation enzymes and carbohydrate-protein interactions.

Basic Information

Product Name	2-C-(2,3,4,6-Tetra-O-Acetyl-β-D-Glucopyranosyl) Ethyne
CAS No.	168105-32-6
Molecular Formula	C₁₆H₂₀O₁₀
Molecular Weight	372.32 g/mol
Synonyms	2-C-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)acetylene; 2-C-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)ethyne; 2-C-(Tetra-O-acetyl-β-D-glucopyranosyl)ethyne; 2-C-(Peracetyl-β-D-glucopyranosyl)ethyne; 2-C-(β-D-Glucopyranosyl-2,3,4,6-tetraacetate)ethyne; 1,2,3,4,6-Penta-O-acetyl-β-D-glucopyranosyl acetylene derivative; Protected glucosyl alkyne; Acetylated glucosyl acetylene
EINECS	Contact for details

Quality Control

Our 2-C-(2,3,4,6-Tetra-O-Acetyl-β-D-Glucopyranosyl) Ethyne is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.