Description

P58 Natural Killer Cell Receptor is a specialized peptide or protein fragment designed to interact with specific receptors on Natural Killer (NK) cells. This compound is critical for immunological research and therapeutic development, enabling the study and modulation of NK cell activity. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in immunology, oncology, and cell therapy R&D.

Application

• Immunological Research: Used as a key reagent to study NK cell activation, inhibition, and signaling pathways in vitro.
• Drug Discovery & Screening: Serves as a target or tool compound in high-throughput assays for developing novel immunotherapies.
• Cell-Based Assay Development: Essential for functional assays measuring NK cell cytotoxicity and cytokine release.
• Therapeutic Antibody & Biologic Development: Acts as a reference standard or blocking agent in the characterization of monoclonal antibodies targeting NK cell receptors.
• Cancer Research: Investigated for its role in tumor immune evasion and for developing NK cell-engaging therapeutic strategies.
• Receptor-Ligand Interaction Studies: Employed in surface plasmon resonance (SPR) or ELISA-based binding studies to determine affinity and kinetics.

Basic Information

Product Name	P58 Natural Killer Cell Receptor
CAS No.	167975-17-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NK Cell Receptor P58; P58 NK Receptor; Natural Killer Cell Inhibitory Receptor P58; CD158b; KIR2DL2; KIR2DL3; Killer Cell Immunoglobulin-Like Receptor 2DL2/3; Ly-49 (murine homolog reference)
EINECS	Contact for details

Quality Control

Our P58 Natural Killer Cell Receptor is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive suite of analytical techniques, including HPLC for purity, mass spectrometry for identity confirmation, and functional bioassays. A Certificate of Analysis (COA) detailing purity, identity, endotoxin levels, and biological activity is provided with each batch to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles. Handle under aseptic conditions where applicable.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95%
Endotoxin Level (LAL)	< 1.0 EU/mg
Biological Activity (Cell-based Assay)	Contact for details
Solubility	Soluble in PBS or sterile water for injection

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.