Description

Carbamic Acid, (3-Methyl-3-Pyrrolidinyl)-, 1,1-Dimethylethyl Ester, (-)- (9Ci) is a high-purity, chiral chemical intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key building block for the synthesis of complex, biologically active molecules, particularly in the pharmaceutical sector. This compound is essential for research and development chemists and process scale-up teams working on novel therapeutics, including central nervous system (CNS) agents and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of advanced drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block to introduce the (3-methyl-3-pyrrolidinyl) moiety with defined stereochemistry into target molecules.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of commercial-scale manufacturing routes for target compounds.
• Fine Chemical Production: Utilized in the synthesis of other high-value, specialty fine chemicals requiring this specific chiral amine derivative.

Basic Information

Product Name	Carbamic Acid, (3-Methyl-3-Pyrrolidinyl)-, 1,1-Dimethylethyl Ester, (-)- (9Ci)
CAS No.	167888-17-7
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	(-)-tert-Butyl 3-methylpyrrolidine-3-carboxylate; (3R)-3-Methylpyrrolidine-3-carboxylic acid tert-butyl ester; (R)-tert-Butyl 3-methyl-3-pyrrolidinecarboxylate; tert-Butyl (R)-3-methylpyrrolidine-3-carboxylate; (R)-1-Boc-3-methyl-3-pyrrolidinecarboxylic acid tert-butyl ester; 1-Boc-3-methyl-3-pyrrolidinecarboxylic acid tert-butyl ester; (R)-1-(tert-Butoxycarbonyl)-3-methylpyrrolidine-3-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Methyl-3-Pyrrolidinyl)-, 1,1-Dimethylethyl Ester, (-)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.