Description

Z-Arg-Leu-Arg-Gly-Gly-Amc CAS NO 167698-69-3 is a specialized fluorogenic peptide substrate designed for high-sensitivity enzymatic assays. This compound is critical for researchers and developers in the life sciences sector who require precise tools for studying protease activity and kinetics. It is primarily utilized in biochemical research, pharmaceutical development, and diagnostic applications where accurate measurement of enzyme function is paramount.

Application

• Protease Research & Assay Development: Acts as a selective fluorogenic substrate for studying the activity and inhibition of specific proteases, including trypsin-like enzymes.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and characterize potential therapeutic protease inhibitors for drug discovery programs.
• Biochemical Mechanism Studies: Enables detailed kinetic analysis and mechanistic studies of enzymatic cleavage pathways in vitro.
• Diagnostic Reagent Component: Serves as a key component in the formulation of sensitive diagnostic kits for detecting protease-related biomarkers.
• Cell Biology & Physiology Research: Employed to monitor protease activity in cellular and tissue models to understand their role in physiological and pathological processes.

Basic Information

Product Name	Z-Arg-Leu-Arg-Gly-Gly-Amc
CAS No.	167698-69-3
Molecular Formula	C34H55N13O9
Molecular Weight	765.88 g/mol
Synonyms	Z-Arg-Leu-Arg-Gly-Gly-AMC; Z-RLRGG-AMC; Benzyloxycarbonyl-Arg-Leu-Arg-Gly-Gly-7-Amino-4-methylcoumarin; Boc-Arg-Leu-Arg-Gly-Gly-Amc (common alternate); Fluorogenic Substrate for Trypsin-like Proteases; Protease Substrate 167698-69-3; Z-R-L-R-G-G-AMC
EINECS	Contact for details

Quality Control

Every batch of Z-Arg-Leu-Arg-Gly-Gly-Amc is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and performance consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as HPLC purity, water content, and functional activity in standard assays. Our quality commitment aligns with the standards expected for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Functional Activity	Conforms to reference standard in enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.