Description

Fmoc-Tranexamic Acid CAS NO 167690-53-1 is a protected derivative of the antifibrinolytic agent tranexamic acid, featuring the 9-fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino functionality. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of tranexamic acid into peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, hemostatic agents, and protease inhibitors.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative, it serves as a key intermediate for the automated synthesis of peptides containing tranexamic acid motifs.
• Pharmaceutical Research & Development: Used in the discovery and development of novel peptide-based drugs targeting bleeding disorders, inflammation, and wound healing.
• Protease Inhibitor Design: Acts as a scaffold for creating inhibitors of serine proteases like plasmin, which are involved in fibrinolysis and other physiological processes.
• Bioconjugation and Probe Development: The reactive carboxyl group allows for conjugation to other molecules, useful in creating fluorescent probes or affinity labels for biochemical studies.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of tranexamic acid derivatives.

Basic Information

Product Name	Fmoc-Tranexamic Acid
CAS No.	167690-53-1
Molecular Formula	C19H19NO5
Molecular Weight	341.36 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-(aminomethyl)cyclohexanecarboxylic Acid; Fmoc-Tranexamic Acid; Fmoc-4-(Aminomethyl)cyclohexanecarboxylic Acid; N-Fmoc-tranexamic acid; (4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]aminomethyl}cyclohexyl)carboxylic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-Tranexamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.