Description

(2,5-Difluorophenyl)Acetic Acid Methyl Ester is a high-purity fluorinated aromatic ester, a key building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which significantly influences the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis in fine chemical production.
• Custom Synthesis & Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical entities in medicinal and material chemistry.

Basic Information

Product Name	(2,5-Difluorophenyl)Acetic Acid Methyl Ester
CAS No.	167484-38-0
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	Methyl (2,5-difluorophenyl)acetate; 2-(2,5-Difluorophenyl)acetic acid methyl ester; Methyl 2-(2,5-difluorophenyl)acetate; (2,5-Difluorobenzene)acetic acid methyl ester; 2,5-Difluorophenylacetic acid methyl ester; Methyl α-(2,5-difluorophenyl)acetate; 167484-38-0; Methyl (2,5-difluorobenzene)acetate
EINECS	Contact for details

Quality Control

Every batch of (2,5-Difluorophenyl)Acetic Acid Methyl Ester is produced under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.